Outbreak of Aspergillus fumigatus Infection Case Study

Outbreak of Aspergillus fumigatus Infection - Case Study sheathThe first fatality was that of an 85-year-old female who had been leadted was admitted to the hospital in January 1995 for complications associated with chronic renal failure due to nephrosclerosis. Once the contagion was discovered in her lungs, the patients condition declined quickly despite antibiotic regimen. A postmortem exam revealed Aspergillus hyphae in both sides of the lungs.The next fatality was that of a 49-year-old female suffering with Wegener granulomatosis who was admitted in February 1995 for coughing and fever. Once the contagious disease was discovered in her lungs, the patients condition declined rapidly even though immunosuppressive treatments were reduced and antituberculotic therapy instituted. A postmortem exam revealed the Aspergillus infection had spread through the lungs to the heart and into the brain.The near-fatality was that of a 65-year-old male admitted in February 1995 with chronic re nal failure due to renal vascular disease for severe malnutrition. The infection was never discovered in the patients septum but his condition improved with liposomal amphotericin therapy. The patient achieved nearly complete regression in 10 weeks.The study shows certain strengths. The investigators admit the findings are inconclusive especially since they did not test air. They warn that hospital construction or renovation work near immunodepressed patients should alert physicians to the possible heading of A. fumigatus.Likewise, the